Endocrine Abstracts

Aim: The aim of our study was to evaluate the effectiveness of the body mass (BM) decreasing program in pubertal children with alimentary obesity during the year of observation.Materials and methods: Anthropometric changes in body mass index (BMI) and waist circumflex (WC) were analyzed every 1, 3, 6 and 12 months in 100 obese pubertal children (boys/girls =50/50) with different treatment methods: the 1st group – only reducing diet (b/g=30/30), the ...

Materials and methods: We investigated 79 normal (1st group) and 99 overweight (2nd group) preschool children. Deficient sport and average physical activity (APA) duration, risen appetite (point-assessment), prolonged television viewing and computer using time in children were considered as risk-factors of juvenile obesity manifestation. Height, weight, waist circumflex (WC) was measured; body mass index (BMI) was calculated. Serum leptin levels were detected by immunoenzyme m...

Background: Manifestation of early age adiposity raises complicated forms of obesity and risks for concomitant diseases development.Objective: To detect obesogenic risk factors in preschool children screening study.Material and methods: Of 1008 children from 8 Minsk kindergartens were screened. Anthropometrical parameters, systolic and diastolic blood pressure (SBP and DBP) were measured. Body mass index (BMI) standardized for age ...

Background: The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D2 receptor binding (Thompson et al., 1997; Pohjalainen et al.,1998). Associations between Taq1A polymorphism DRD2/ANKK1 gene and reward sensitivity including compulsive overeating were reported (Propper et al., 2008; Davis et al., 2008). To study the association of DRD2/ANKK1 Taq1A polymorphism (rs1800497) with obesity we started g...

Background: Social adaptation difficulty is one of the serious complications in obese children. It manifests with the complex of emotional and behavioral disorders.Aim: To estimate the peculiarities of psychological status, frequency, and severity of depressive disorders in obese children.Methods: We examined 242 children in the in the Endocrinological Department of University Hospital (Minsk); group 1 – 152 obese children (BM...

Background: Binge eating (BE) is a common cause of severe paediatric obesity, which develops after the uncontrolled wish of changing the present emotional condition.Aim: To study the phenomenon of BE in the context of emotional disorders in severe obese children.Methods: We examined 88 children with severe obesity (mean±s.d. 11.5±3.4 years; BMI 29.7±5.7 kg/m2) in the Endocrinological Department of Universi...

Aim: To compare gender frequency of leptin receptor gene (LEPR) genotype rates and leptinemia levels in overweight children.Materials and methods: Three hundred children with adiposity were investigated (divided into groups: prepubertal (1st) m/f n=51/50, early pubertal (2nd) n=49/51, late pubertal (3d) n=50/49). 80 girls and 89 boys with obesity and 90 lean girls and 48 lean boys (control) were genotyped in 6 exon of LEPR gene (Q223...